What comics (including webcomics) have the most distinctive art?
XKCD
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Unix Surrealism
I personally think the art style is very distinctive compared to just about anything else I’ve seen.
Transmetropolitan, though I have a hard time deciding whether is it the style or the characters. Probably both.
Knights of Sidonia was drawn by an architect. Definitely shows - thel background / landscape shots are quite ridiculously good and give you the scope a lot of comics tend to miss.
Darick Robertson’s art is always great.
Order of the Stick
The Other End Comics
Extra Fabulous Comics
Moebius
Nancy.
Quino.
The DaneMen
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For anyone who doesn’t know, this is one of those internet rabbit holes from which not even light can escape.
Nsfw: oglaf.com
God this is gold
Romantically Apocalyptic sticks out in my mind.